© 3P Biotechnologies, Inc.

All materials are the Intellectual Property of 3P Biotechnologies, Inc.

Design and implementation by SKILLET

 

Publications

Exosomes

Munagala R, Aqil F, Jeyabalan J, and Gupta RC. Bovine milk-derived exosomes for drug delivery. Cancer Letters. 371: 48-61, 2016.

 

Aqil F, Kausar H, Agrawal AK, Jeyaprakash J, Munagala R & Gupta RC. Exosomal formulation enhances therapeutic response of celastrol against lung cancer. Experimental and Molecular Pathology. 101: 12-21, 2016.

 

*Agrawal, AK., *Aqil, F.,  Jeyabalan, J., Spencer, WA., Beck, J., Gachuki, BW., Alhakeem, SS., Oben, K., Munagala, R., Bondada, S. and Gupta R. Milk-derived exosomes for oral delivery of paclitaxel. Nanomedicine. S1549-9634 (17) 30043-6, 2017. *(equal contribution)

 

Munagala, R., Aqil, F., Jeyabalan, J., Agrawal, AK., Mudd, A.M., Al-Hassan, K., Vadhanam, MV. and Gupta R. Exosomal formulation of anthocyanidins against multiple cancer types. Cancer Letters.  393: 94-102, 2017.

 

Aqil, F., J Munagala, R., Jeyabalan, J., Agrawal, AK., and Gupta R. Exosomes for the enhanced bioavailability and efficacy of curcumin. The AAPS Journal. 19: 1691-1702, 2017.

 

Aqil F, Jeyabalan J, Agrawal AK, Kyakulaga AH, Parker L, Munagala R, Gupta RC. Exosomal delivery of anthocyanidins for the management of ovarian cancer. Food Funct. 15 8: 4100-4107, 2017.

Aqil F, Munagala R, Jeyabalan J, Agrawal AK, Kyakulaga AH, Wilcher SA, Gupta RC. Milk exosomes – Natural nanoparticles for siRNA delivery. Cancer Letters. 449: 186-195, 2019.

Implantable Devices

Gupta R, Bansal S, Aqil F, Jeyabalan J, Cao P, Kausar H, Russell GK, Munagala R, Ravoori S & Vadhanam MV. Controlled-release systemic delivery - a new concept in cancer chemoprevention. Carcinogenesis. 33:1608–1615, 2012.

 

Bansal SS, Kausar H, Aqil F, Jeyprakash J, Vadhanam MV & Gupta RC. Curcumin implants for continuous systemic delivery: safety and biocompatibility. Drug Deliv. and Transl. Res. 1: 332-341, 2011.

 

Bansal SS, Kausar H, Vadhanam MV, Ravoori S & Gupta  RC. Controlled systemic delivery by polymeric implants enhances tissue and plasma curcumin levels compared with oral administration, Eur.J. Pharm. Biopharm. 80: 571-577, 2012.

 

Aqil F, Vadhanam MV & Gupta RC. Enhanced activity of punicalagin delivered via polymeric implants against benzo[a]pyrene-induced DNA adducts. Mutation Research. 743: 59-66, 2012.

 

Aqil F, Jeyabalan J, Kausar H, Bansal H, Vadahanam MV & Gupta RC. Multi-layer polymeric implants for controlled release of chemopreventives. Cancer Letters, 326: 33-40, 2012.

 

Cao P, Aqil F, Ravoori S, Gupta RC & Vadhanam MV. Polymeric implants for systemic delivery of green tea polyphenols. J. Pharm. Sci, 103, 945-951, 2014

 

Bansal SS, Kausar H, Vadhanam MV, Ravoori S, Rai SN & Gupta RC. Curcumin Implants, not Curcumin Diet Inhibits Estrogen-Induced Mammary Carcinogenesis in ACI Rats. Cancer Prevention Res, 7, 456-465, 2014.

 

*SherwoodLC, *Aqil F, *Vadhanam MV, Jeyabalan J, Hoetkar D, Srivastava S, O’Toole M, Cambron S., Spencer, W, Parker L & Gupta RC. Development of a Large Animal Model for Evaluation of Cervical Implants for the Treatment of Cervical, Vaginal and Vulva Pathologies. Exp Mol Pathol. 103: 320-329, 2017. *(equal contribution)

 

 

Berry ANTHOS™

 

Aiyer HS, Srinivasan C and Gupta RC. Dietary berries and ellagic acid diminish estrogen-mediated mammary tumorigenesis in the ACI rat model. Nutrition & Cancer. 60: 227-234, 2008.

 

Aiyer H & Gupta RC. Berries and ellagic acid prevent estrogen-induced mammary tumorigenesis by modulating enzymes of estrogen metabolism. Cancer Prev Res. 3: 727-737, 2010.

 

Ravoori S, Vadhanam MV, Aqil F & Gupta RC. Inhibition of Estrogen-Mediated Mammary Tumorigenesis by Blueberry and Black Raspberry. J. Agric. Food Chem. 60: 5547−5555, 2012

 

Aqil F, Gupta A, Munagala R, Jeyabalan, J, Kausar H, Sharma, R, Singh IP & Gupta RC. Antioxidant and antiproliferative potential of anthocyanin/ellagitannin-enriched extracts from Syzygium cumini L. (‘jamun’, the Indian Blackberry). Nutrition & Cancer. 64: 428-438, 2012.

 

Kausar H, Jeyabalan J, Aqil F, Chabba D, Sidana J, Singh, IP & Gupta RC. Berry anthocyanidins synergistically suppresses growth and metastatic potential of human non-small-cell lung cancer cells. Cancer Letters. 325: 54-62, 2012.

 

Jeyaprakash J, Aqil, F, Munagala, R. & Gupta RC. Chemopreventive and therapeutic activity of blueberry against estrogen-mediated breast cancer. J. Agric. Food Chem. 62: 3963−3971, 2014.

 

Aqil F, Jeyabalan J, Kausar H, Munagala R & Gupta RC. Therapeutic Activity of Dietary Berries and Polyphenolics against Lung Cancer.  J. Berry Research. 6: 105-114, 2016.